A Novel Approach for Fabrication of Lactose Fibers Using Melt Centrifugal/Rotary Jet Spinning
Category
Sciences and Technology
Department
Chemistry
Student Status
Undergraduate
Research Advisor
Dr. Mazeyar Parvinzadeh Gashti
Document Type
Event
Location
Kansas 2
Start Date
10-4-2025 10:20 AM
End Date
10-4-2025 10:20 AM
Description
Lactose is a naturally occurring disaccharide composed of one molecule of glucose and one molecule of galactose. It is primarily found in milk and dairy products and has various applications in the food and pharmaceutical industries.
Due to its non-toxic nature, we aimed to fabricate lactose fibers using the melt centrifugal/rotary jet spinning (MCRJS) process and assess their potential biological properties.
For this purpose, we fabricated lactose fibers and incorporated stearyl glycyrrhetinate as an active ingredient to evaluate its effects. Stearyl glycyrrhetinate, derived from licorice root, is known for its anti-inflammatory, antioxid ant, and skin-soothing properties.
The properties of stearyl glycyrrhetinate-loaded lactose fibers were assessed using Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD), and Fourier Transform Infrared Spectroscopy (FTIR). Additionally, the biological properties of the fabricated lactose fibers were evaluated through microbial culture testing. FTIR spectroscopy confirmed chemical interactions between stearyl glycyrrhetinate and lactose molecules. The composite fibers also demonstrated antimicrobial properties, making them promising candidates for various biomedical applications, such as wound dressings, tissue scaffolds, and controlled drug release systems. These findings highlight the potential of the MCRJS process for producing biocompatible lactose-based fibers and emphasize the versatility of this technique in developing fibrous materials.
A Novel Approach for Fabrication of Lactose Fibers Using Melt Centrifugal/Rotary Jet Spinning
Kansas 2
Lactose is a naturally occurring disaccharide composed of one molecule of glucose and one molecule of galactose. It is primarily found in milk and dairy products and has various applications in the food and pharmaceutical industries.
Due to its non-toxic nature, we aimed to fabricate lactose fibers using the melt centrifugal/rotary jet spinning (MCRJS) process and assess their potential biological properties.
For this purpose, we fabricated lactose fibers and incorporated stearyl glycyrrhetinate as an active ingredient to evaluate its effects. Stearyl glycyrrhetinate, derived from licorice root, is known for its anti-inflammatory, antioxid ant, and skin-soothing properties.
The properties of stearyl glycyrrhetinate-loaded lactose fibers were assessed using Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD), and Fourier Transform Infrared Spectroscopy (FTIR). Additionally, the biological properties of the fabricated lactose fibers were evaluated through microbial culture testing. FTIR spectroscopy confirmed chemical interactions between stearyl glycyrrhetinate and lactose molecules. The composite fibers also demonstrated antimicrobial properties, making them promising candidates for various biomedical applications, such as wound dressings, tissue scaffolds, and controlled drug release systems. These findings highlight the potential of the MCRJS process for producing biocompatible lactose-based fibers and emphasize the versatility of this technique in developing fibrous materials.
