Date of Award

1933

Document Type

Thesis

Degree Name

Master of Science (MS)

Department

Biology

First Advisor

George M. Plagens

Keywords

Mice -- Anatomy. Muscles. Extremities (Anatomy) -- Muscles

Abstract

One of the most important and much disputed questions in the field of developmental anatomy is the role the myotomes play in the development of the limb musculature. At present there are two explanations advanced concerning the development of the limb-musculature in mammals. The first is that limb-buds arise as local thickening of the somatopleure, which becomes filled with a homogeneous syncytial mesenchymal tissue, that later becomes innervated with muscle-buds from the myotomes and with blood vessels, and nerves from the trunk of th embryo. The second method explained as to the origin of limb muscles is that they are simply differentiated from the mesenchyma of the limb-buds with no relation to the myotomes.

The purpose of this paper is not to establish dogmatic evidence as to which method of development is correct, but to describe the embryonic origin and development of the limb-muscles i the mouse. [Taken from introduction]

Included in

Biology Commons

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