Date of Award
8-1994
Document Type
Thesis
Degree Name
Master of Science (MS)
First Advisor
J. Ralph Wells
Keywords
Helminths, Physiology, Heterophile, Antigens
Abstract
One of the many interesting, as well as significant observations in immunological research was the discovery of the so-called heterophile antigen by Forssman (1911). Until this observation was reported, immunity had been considered specific in the sense that an antigen from one species would stimulate the production of antibody capable of reacting only with the homologous antigen or the same antigen from another individual of the same species. When, however, Forssman observed that mascerated guinea pig kidney (antigen) when injected into rabbits stimulated the production of antibody which hemolyzed sheep red corpuscles, an element of doubt was introduced into the question of specificity or antigen-antibody reactions. This doubt was soon intensified by numerous other investigations of a similar nature, in which it was shown that this phenomenon is more common than one might have supposed it to be (Bull 1928). […]
Recommended Citation
Trimmell, John A., "Heterophile antigen in some of the common helminths" (1994). Electronic Theses & Dissertations. 687.
https://digitalcommons.pittstate.edu/etd/687
